Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462866 | 0.78 | KDM4E (0.64) | KDM4EGAAHTT | |
| SCHEMBL17555848 | 0.73 | HRH4 (0.53) | KDM4EGAAHRH4 | |
| SCHEMBL16040576 | 0.73 | HRH4 (0.60) | HTTHRH4NSD2PKMPIK3CA | |
| SCHEMBL18032425 | 0.73 | HRH4 (0.48) | HTTHRH4NSD2PKMPIK3CA | |
| SCHEMBL30828999 | 0.72 | HTT (0.56) | GAAHTTHRH4NSD2PKM | |
| SCHEMBL26647139 | 0.72 | HTT (0.56) | GAAHTTHRH4NSD2PKM | |
| SCHEMBL17622695 | 0.72 | HRH4 (0.51) | KDM4EHTTHRH4NSD2PKM | |
| SCHEMBL2402476 | 0.71 | HRH4 (0.50) | HTTHRH4NSD2PKM | |
| SCHEMBL9159049 | 0.71 | HTT (0.61) | KDM4EGAAHTTPKMPIK3CA | |
| Hydrochloric Acid SCHEMBL6250468 | 0.70 | HRH4 (0.53) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728644-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0168500-A1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-01-22 | — | — | EP | disclosed |