Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.48 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670296 | 0.91 | MAPK14 (0.49) | MAPK14SNRNP200MEN1ALDH1A1HPGD | |
| SCHEMBL9652539 | 0.80 | MAPK14 (0.49) | MAPK14SNRNP200MEN1ALDH1A1HPGD | |
| SCHEMBL10674817 | 0.78 | MAPK14 (0.52) | MAPK14SNRNP200MEN1ALDH1A1HPGD | |
| SCHEMBL9662923 | 0.78 | SRD5A2 (0.47) | MEN1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL10665233 | 0.77 | MAPK14 (0.49) | MAPK14SNRNP200MEN1ALDH1A1HPGD | |
| SCHEMBL10664803 | 0.77 | SNRNP200 (0.40) | MAPK14SNRNP200MEN1KMT2ANOTUM | |
| SCHEMBL29067974 | 0.77 | SRD5A2 (0.47) | MAPK14MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL12949558 | 0.76 | MRGPRX4 (0.41) | MEN1KMT2APTGER1NOTUM | |
| SCHEMBL988041 | 0.76 | MRGPRX4 (0.42) | MAPK14MEN1KMT2APTGER1NOTUM | |
| SCHEMBL2115801 | 0.76 | SRD5A2 (0.51) | MEN1KMT2APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772693-A | 2-oxo-1-((Substituted sulfonyl)amino)-carbonyl)azetidines | E. R. SQUIBB & SONS, INC. (US) | 1988-09-20 | — | — | US | disclosed |