Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670296 | 0.86 | MAPK14 (0.49) | SRD5A2SRD5A1NOTUMALDH1A1PTGER1 | |
| SCHEMBL2115801 | 0.84 | SRD5A2 (0.51) | SRD5A2SRD5A1MRGPRX4BRD4PTGER1 | |
| SCHEMBL28499829 | 0.82 | COMT (0.49) | BRD4ALDH1A1MAPK14NPC1RAB9A | |
| SCHEMBL988041 | 0.81 | MRGPRX4 (0.42) | SRD5A2SRD5A1MRGPRX4NOTUMPTGER1 | |
| SCHEMBL12949558 | 0.81 | MRGPRX4 (0.41) | SRD5A2SRD5A1MRGPRX4NOTUMBRD4 | |
| SCHEMBL9662923 | 0.81 | SRD5A2 (0.47) | SRD5A2SRD5A1MRGPRX4ALDH1A1PTGER1 | |
| SCHEMBL14124908 | 0.78 | FOLH1 (0.46) | SRD5A2SRD5A1ALDH1A1PTGER1HPGD | |
| SCHEMBL10668010 | 0.77 | MAPK14 (0.48) | NOTUMALDH1A1PTGER1MAPK14HPGD | |
| SCHEMBL28500762 | 0.76 | COMT (0.53) | BRD4PTGER1MAPK14 | |
| SCHEMBL28508801 | 0.75 | COMT (0.52) | BRD4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |