Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 14/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509731 | 0.82 | ACE (0.66) | TSHRACEACE2 | |
| SCHEMBL9551626 | 0.82 | ACE (0.66) | TSHRACEACE2 | |
| SCHEMBL10668559 | 0.81 | ACE (0.68) | TSHRACEACE2 | |
| SCHEMBL22811348 | 0.79 | PREP (0.69) | ACEACE2 | |
| SCHEMBL22209470 | 0.79 | PREP (0.69) | ACEACE2 | |
| SCHEMBL9509127 | 0.78 | ACE (0.63) | TSHRACEACE2 | |
| SCHEMBL30905695 | 0.77 | ACE (0.48) | ACEACE2 | |
| SCHEMBL10830758 | 0.77 | TSHR (0.62) | TSHRACEACE2 | |
| SCHEMBL10830200 | 0.77 | TSHR (0.62) | TSHRACEACE2 | |
| SCHEMBL15251975 | 0.77 | ACE (0.70) | TSHRACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| US-4695582-A | Inhibitors of angiotensin converting enzyme | UNIVERSITY OF MIAMI (US) | 1987-09-22 | — | — | US | disclosed |