Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668631 | 1.00 | GLO1 (0.71) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7435949 | 0.88 | GLO1 (0.75) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7435954 | 0.88 | GLO1 (0.75) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8018753 | 0.88 | GLO1 (0.90) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL11681247 | 0.85 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL10668637 | 0.84 | GLO1 (0.62) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7475824 | 0.83 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7475820 | 0.83 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL10757963 | 0.83 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7428618 | 0.83 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769375-A | Circulation-active 1,4-dihydropyridine derivatives and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-06 | — | — | US | disclosed |