Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 9/20 | 0.43 |
| ▸ | CDK4 | P11802 | 5/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965751 | 0.79 | — | — | |
| SCHEMBL924920 | 0.78 | ALDH1A1 (0.51) | KMT2ACDK2CDK4CCNA2PLK1 | |
| SCHEMBL18774053 | 0.75 | — | — | |
| SCHEMBL14489682 | 0.75 | — | — | |
| SCHEMBL29941155 | 0.74 | CDK2 (0.53) | KMT2ACDK2CDK4CCNA2PLK1 | |
| SCHEMBL924644 | 0.74 | CDK2 (0.50) | KMT2ACDK2CDK4CCNA2PLK1 | |
| SCHEMBL925797 | 0.73 | CYP3A4 (0.51) | KMT2ACDK2CDK4CCNA2PLK1 | |
| SCHEMBL4169064 | 0.72 | CDK2 (0.68) | CDK2CDK4CCNA2PLK1MAPT | |
| SCHEMBL11916724 | 0.72 | KMT2A (0.48) | KMT2ACDK2CDK4CCNA2ALDH1A1 | |
| SCHEMBL19457067 | 0.72 | TMIGD3 (0.51) | KMT2ACDK2CDK4CCNA2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4735957-A | ANTIULCER AGENTS, CARDIOTONIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4649146-A | ANTIULCER | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0117082-A2 | Thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-29 | — | — | EP | disclosed |