SCHEMBL10669290

SCHEMBL10669290

O=C(c1ccc(O)cc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SRD5A2 P31213 5/20 0.75
▸ LTA4H P09960 1/20 0.72
▸ NR1H2 P55055 1/20 0.72
▸ BAX Q07812 1/20 0.72
▸ MEN1 O00255 3/20 0.62
▸ KMT2A Q03164 3/20 0.62
▸ LMNA P02545 2/20 0.62
▸ MAPT P10636 2/20 0.62
▸ RAB9A P51151 2/20 0.62
▸ PARP10 Q53GL7 2/20 0.60
▸ ESR1 P03372 2/20 0.60
▸ ESR2 Q92731 2/20 0.60
▸ PKM P14618 1/20 0.60
▸ HPGD P15428 1/20 0.60
▸ HTT P42858 1/20 0.60
▸ POLB P06746 1/20 0.57
▸ NPC1 O15118 1/20 0.55
▸ ELANE P08246 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19406167 0.98 SRD5A2 (0.72) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL24421676 0.96 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL18401385 0.96 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL24421578 0.96 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL7938036 0.96 SRD5A2 (0.69) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL8071074 0.92 MAPT (0.71) SRD5A2LTA4HNR1H2BAXMEN1
SCHEMBL9536469 0.92 SRD5A2 (0.88) SRD5A2LTA4HNR1H2BAXPARP10
SCHEMBL235530 0.92 SRD5A2 (0.88) SRD5A2LTA4HNR1H2BAXPARP10
SCHEMBL2866068 0.92 SRD5A2 (0.88) SRD5A2LTA4HNR1H2BAXPARP10
SCHEMBL1082112 0.92 SRD5A2 (0.88) SRD5A2LTA4HNR1H2BAXPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024104139-A1 COMPOSITE MATERIAL, LIGHT-EMITTING DEVICE COMPRISING SAME, AND PREPARATION METHOD THEREFOR TCL科技集团股份有限公司 2024-05-23 — — WO claimed
CN-118057941-A Composite material, light-emitting device comprising composite material, preparation method of light-emitting device and display device TCL科技集团股份有限公司 2024-05-21 — — CN claimed
US-4794155-A Process for forming arylether polymers THE DOW CHEMICAL COMPANY (US) 1988-12-27 — — US claimed
WO-2024223752-A1 LUBRICANT COMPOSITION PHOENIX CONTACT GMBH & CO. KG (DE) 2024-10-31 — — WO disclosed
WO-2024104139-A1 COMPOSITE MATERIAL, LIGHT-EMITTING DEVICE COMPRISING SAME, AND PREPARATION METHOD THEREFOR TCL科技集团股份有限公司 2024-05-23 — — WO disclosed
CN-118057941-A Composite material, light-emitting device comprising composite material, preparation method of light-emitting device and display device TCL科技集团股份有限公司 2024-05-21 — — CN disclosed
EP-4235867-A1 METHOD FOR OPERATING A DEVICE COMPRISING AT LEAST ONE ELECTRIC PRIMARY CELL CONTAINING SILICON, AN ELECTROCHEMICAL PRIMARY CELL, A SYSTEM COMPRISING THE DEVICE AND A COMPUTER IMPLEMENTED METHOD Evonik Operations GmbH (DE) 2023-08-30 — — EP disclosed
EP-3448299-B1 FLEXIBLE DENTAL BASIC STRUCTURE FOR SECURING DENTAL PROSTHETIC FIXTURES TO IMPLANTS KULZER & CO GMBH (DE) 2021-07-14 — — EP disclosed
US-10934303-B2 Aryl ethene derivative and pharmaceutical composition containing same as active ingredient DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2021-03-02 — — US disclosed
WO-2020138265-A1 METHOD, APPARATUS AND PROGRAM FOR ASSESSING AMYLOID FORMATION 国立大学法人室蘭工業大学 2020-07-02 — — WO disclosed
US-20190167820-A1 NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT HWANG SUNG YEOUN (KR) 2019-06-06 — — US disclosed
US-20140179891-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 — — US disclosed
WO-2014100635-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 — — WO disclosed
US-4794155-A Process for forming arylether polymers THE DOW CHEMICAL COMPANY (US) 1988-12-27 — — US disclosed
EP-0128692-B1 PROCESS FOR THE PREPARATION OF 4-HYDROXY-BENZOPHENONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-02 — — EP disclosed
EP-0128693-B1 PROCESS FOR THE PREPARATION OF 4-HYDROXYBENZOPHENONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-01-27 — — EP disclosed
US-4604485-A Chemical process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-08-05 — — US disclosed
US-4599452-A Chemical process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-07-08 — — US disclosed
EP-0128693-A2 Process for the preparation of 4-hydroxybenzophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-19 — — EP disclosed
EP-0128692-A2 Process for the preparation of 4-hydroxy-benzophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190167820-A1 NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT ESRRG, ESR2, ESR1 SRD5A2 119/4885LTA4H 931/4885NR1H2 15/4885
US-10934303-B2 Aryl ethene derivative and pharmaceutical composition containing same as active ingredient ESRRG, ESR1, ESR2 SRD5A2 124/4885LTA4H 702/4885NR1H2 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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