Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526679 | 0.92 | GRM5 (0.60) | GRM5APPMAPTFFAR1HNF4A | |
| SCHEMBL8577931 | 0.81 | GRM5 (0.61) | GRM5APPMAPTFFAR1HNF4A | |
| SCHEMBL14586701 | 0.80 | GRM5 (0.51) | GRM5FFAR1SRD5A1SRD5A2 | |
| SCHEMBL14586702 | 0.80 | GRM5 (0.51) | GRM5FFAR1SRD5A1SRD5A2 | |
| SCHEMBL10190650 | 0.77 | GRM5 (1.00) | GRM5SRD5A1 | |
| SCHEMBL8911138 | 0.76 | GRM5 (0.56) | GRM5APPMAPTSRD5A2 | |
| SCHEMBL2114741 | 0.75 | APP (0.92) | GRM5APPMAPTFFAR1HNF4A | |
| Diphenylacetylene SCHEMBL27628902 | 0.75 | APP (0.92) | GRM5APPMAPTFFAR1HNF4A | |
| SCHEMBL14032816 | 0.74 | GRM5 (0.56) | GRM5FFAR1SRD5A1 | |
| SCHEMBL4517848 | 0.74 | GRM5 (0.46) | GRM5MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4724260-A | Unsaturated alkyl monoarylcyclobutane monomers | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | claimed |
| US-4783514-A | Polymeric monoarylcyclobutane compositions | THE DOW CHEMICAL COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4724260-A | Unsaturated alkyl monoarylcyclobutane monomers | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |