Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669654 | 1.00 | MEN1 (0.43) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10665991 | 0.88 | MEN1 (0.51) | MEN1KMT2APOLBCYP1A2ALOX15 | |
| SCHEMBL4341585 | 0.88 | MEN1 (0.51) | MEN1KMT2APOLBCYP1A2ALOX15 | |
| SCHEMBL10666390 | 0.87 | KMT2A (0.42) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10669710 | 0.87 | MEN1 (0.42) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10666382 | 0.87 | KMT2A (0.42) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10665793 | 0.87 | KMT2A (0.42) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10665494 | 0.87 | MEN1 (0.42) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10660797 | 0.84 | RAB9A (0.43) | MEN1KMT2APOLBGAARAB9A | |
| SCHEMBL10660786 | 0.84 | RAB9A (0.43) | MEN1KMT2APOLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775675-A | Thiazolidinecarboxylic acid derivatives and treatment of liver diseases therewith | BIOGAL GYOGYSZERGYAR (HU) | 1988-10-04 | — | — | US | disclosed |