Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.53 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676936 | 1.00 | ABCC8 (0.53) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10680728 | 0.99 | ABCC8 (0.51) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10674797 | 0.94 | ABCC8 (0.49) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10680686 | 0.93 | ABCC8 (0.48) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10678354 | 0.93 | KCNQ2 (0.48) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10673886 | 0.93 | KCNQ2 (0.53) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10673063 | 0.93 | KCNQ2 (0.48) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10671654 | 0.92 | ABCC8 (0.49) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10673622 | 0.92 | ABCC8 (0.51) | ABCC8LMNASLC22A1ABCC3ABCC4 | |
| SCHEMBL10675815 | 0.91 | ABCC8 (0.47) | ABCC8LMNASLC22A1ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | disclosed |