Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498016 | 0.87 | — | — | |
| SCHEMBL1799678 | 0.73 | ALDH1A1 (0.63) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL9825171 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL9454448 | 0.69 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL2697714 | 0.67 | ALDH1A1 (0.36) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL28770584 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL6462643 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL394300 | 0.66 | TAAR1 (0.76) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL1607063 | 0.66 | ALDH1A1 (0.39) | ALDH1A1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL9454254 | 0.64 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| US-4721712-A | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents | PFIZER INC. (US) | 1988-01-26 | — | — | US | disclosed |
| US-4658037-A | RHEUMATIC DISEASES | PFIZER INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4569942-A | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents | PFIZER INC. (US) | 1986-02-11 | — | — | US | disclosed |