Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672558 | 0.80 | ALDH1A1 (0.49) | CYP19A1CYP11B1CYP11B2DHODHCYP17A1 | |
| SCHEMBL12015399 | 0.75 | PTPN11 (0.55) | CYP19A1CYP11B1CYP11B2ALOX15HTT | |
| SCHEMBL14496874 | 0.74 | PTPN11 (0.51) | CYP19A1CYP11B1CYP11B2DHODHALOX15 | |
| SCHEMBL5776604 | 0.73 | PTPN11 (0.54) | CYP19A1CYP11B1CYP11B2DHODHALOX15 | |
| SCHEMBL20612436 | 0.73 | PTPN11 (0.50) | CYP19A1CYP11B1CYP11B2CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL10631732 | 0.72 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2CYP3A4ALOX15 | |
| SCHEMBL69025 | 0.72 | PTPN11 (0.68) | CYP19A1CYP11B1CYP11B2ALOX15HTT | |
| SCHEMBL29365729 | 0.72 | PTPN11 (0.68) | CYP19A1CYP11B1CYP11B2ALOX15HTT | |
| SCHEMBL16485169 | 0.72 | PTPN11 (0.53) | CYP19A1CYP11B1CYP11B2CYP3A4ALOX15 | |
| SCHEMBL7440151 | 0.72 | PTPN11 (0.53) | CYP19A1CYP11B1CYP11B2DHODHALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778817-A | INHIBIT THROMBOXANE SYNTHETASE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |