Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | APEX1 | P27695 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160973 | 1.00 | NR1I2 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10673255 | 1.00 | NR1I2 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10673324 | 0.93 | NR1I2 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10678869 | 0.91 | NR1I2 (0.67) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10678864 | 0.91 | NR1I2 (0.67) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10673536 | 0.91 | NR1I2 (0.50) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10936533 | 0.91 | NR1I2 (0.52) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10673518 | 0.91 | NR1I2 (0.50) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10936510 | 0.91 | NR1I2 (0.52) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10668996 | 0.91 | NR1I2 (0.49) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736039-A | ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4649136-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0071891-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |
| US-4515788-A | BACTERICIDAL ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-07 | — | — | US | disclosed |