Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.62 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160973 | 0.93 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10673263 | 0.93 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10673255 | 0.93 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10676259 | 0.91 | NR1I2 (0.67) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10938717 | 0.90 | NR1I2 (0.49) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10936533 | 0.89 | NR1I2 (0.52) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10673536 | 0.89 | NR1I2 (0.50) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10936510 | 0.89 | NR1I2 (0.52) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10673518 | 0.89 | NR1I2 (0.50) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10671707 | 0.89 | TDP1 (0.49) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736039-A | ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4649136-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0071891-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |
| US-4515788-A | BACTERICIDAL ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0071891-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |