Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672193 | 0.90 | KMT2A (0.70) | MEN1KMT2APGRALDH1A1KDM4E | |
| SCHEMBL29972879 | 0.88 | KMT2A (0.71) | MEN1KMT2APGRALDH1A1KDM4E | |
| SCHEMBL1446261 | 0.88 | KMT2A (0.71) | MEN1KMT2APGRALDH1A1KDM4E | |
| SCHEMBL10673230 | 0.84 | KMT2A (0.61) | MEN1KMT2APGRALDH1A1KDM4E | |
| SCHEMBL10671563 | 0.82 | KMT2A (0.65) | MEN1KMT2APGRALDH1A1KDM4E | |
| Roquinimex SCHEMBL42132 | 0.79 | KMT2A (1.00) | MEN1KMT2APGRALDH1A1KDM4E | |
| Roquinimex SCHEMBL29359144 | 0.79 | KMT2A (1.00) | MEN1KMT2APGRALDH1A1KDM4E | |
| Roquinimex SCHEMBL8169579 | 0.79 | KMT2A (1.00) | MEN1KMT2APGRALDH1A1KDM4E | |
| SCHEMBL19628902 | 0.78 | MEN1 (0.48) | MEN1KMT2APGRALDH1A1KDM4E | |
| SCHEMBL10676909 | 0.77 | MEN1 (0.56) | MEN1KMT2APGRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738971-A | ENHANCED CELL-MEDIATED IMMUNITY; ANTIARTHRITIC AGENTS; NONTOXIC | AKTIEBOLASET LEO (SE) | 1988-04-19 | — | — | US | disclosed |
| US-4547511-A | FOR ENHANCIN CELL-MEDIATED IMMUNITY | AKTIEBOLAGET LEO (SE) | 1985-10-15 | — | — | US | disclosed |
| EP-0059698-B1 | HETEROCYCLIC CARBOXAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND METHODS OF TREATMENT THEREWITH | AB LEO (SE) | 1985-09-25 | — | — | EP | disclosed |
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |