Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722437 | 0.93 | MEN1 (0.46) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| Paquinimod SCHEMBL29362498 | 0.91 | MEN1 (0.50) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| Paquinimod SCHEMBL1573633 | 0.91 | MEN1 (0.50) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| Paquinimod SCHEMBL1573462 | 0.90 | MEN1 (0.49) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| Paquinimod SCHEMBL1573731 | 0.90 | MEN1 (0.49) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| Paquinimod SCHEMBL1573653 | 0.90 | MEN1 (0.49) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| Paquinimod SCHEMBL1573460 | 0.90 | MEN1 (0.49) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| SCHEMBL7600507 | 0.88 | MEN1 (0.47) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| SCHEMBL7600409 | 0.86 | HDAC4 (0.57) | MEN1KMT2APGRHDAC4ALDH1A1 | |
| SCHEMBL7612167 | 0.86 | MEN1 (0.46) | MEN1KMT2APGRHDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | Westfaelische Wihelms-Universitaet Muenster (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20170333577-A1 | QUINOLINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE IN DIAGNOSIS | Westfälische Wilhelms-Universität Münster (DE) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | S100A9, S100A4, S100A10 | MEN1 3766/4885KMT2A 3628/4885PGR 4606/4885 |
| US-20170333577-A1 | QUINOLINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE IN DIAGNOSIS | S100A9, S100A4, S100A10 | MEN1 3766/4885KMT2A 3628/4885PGR 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.