SCHEMBL1067359

SCHEMBL1067359

C=CC(=O)OC(CC)[Si](C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.36
HPGD P15428 1/20 0.35
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16538072 0.86 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3832655 0.86 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL134911 0.84 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5839195 0.84 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL110060 0.84 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11118154 0.84 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16537401 0.83 TSHR (0.45) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL5838258 0.83 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16538024 0.83 TSHR (0.34) TSHRHPGD
SCHEMBL28174418 0.83 TSHR (0.38) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US claimed
EP-4735538-A1 1K COATING COMPOSITION AND COATED ARTICLE Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) 2026-05-06 EP claimed
WO-2025039831-A1 1K COATING COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2025-02-27 WO claimed
CN-119351033-A Electrically detachable single-component siloxane modified heat-conducting polyurethane hot melt adhesive and preparation method and application thereof 韦尔通科技股份有限公司 2025-01-24 CN claimed
CN-119350983-A Electrically detachable acrylate modified polyurethane hot melt adhesive and preparation method and application thereof 韦尔通科技股份有限公司 2025-01-24 CN claimed
CN-119193082-A Polyurethane hot melt adhesive with excellent adhesive property and electric disassembly, and preparation method and application thereof 韦尔通科技股份有限公司 2024-12-27 CN claimed
CN-118909367-A Low-temperature-resistant PVC plastic and preparation method thereof 浙江金立达新材料科技股份有限公司 2024-11-08 CN claimed
EP-4253466-B1 RUBBER COMPOSITION, VULCANIZED OBJECT OBTAINED FROM SAID RUBBER COMPOSITION, AND VULCANIZED MOLDED OBJECT OBTAINED FROM SAID RUBBER COMPOSITION DENKA COMPANY LTD (JP) 2024-10-02 EP claimed
CN-114245812-B Latex for bonding fibrous structures 昕特玛德国有限公司 2024-08-23 CN claimed
CN-118406462-A UV moisture dual-curing polyurethane sealant and preparation method and application thereof 韦尔通科技股份有限公司 2024-07-30 CN claimed
EP-1360254-B2 ABSORBENT, LUBRICIOUS COATING AND ARTICLES COATED THEREWITH KIMBERLY CLARK CO (US) 2012-12-26 EP claimed
EP-1751197-B1 GEOSYNTHETIC COMPOSITE FOR BOREHOLE STRENGTHENING SHELL INT RESEARCH (NL) 2009-11-11 EP claimed
EP-1826239-B1 Curable composition and coated article SHINETSU CHEMICAL CO (JP) 2009-08-26 EP claimed
EP-1360254-B1 ABSORBENT, LUBRICIOUS COATING AND ARTICLES COATED THEREWITH KIMBERLY CLARK CO (US) 2008-07-02 EP claimed
EP-1401634-B1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE ESSILOR INT (FR) 2006-10-04 EP claimed
EP-1395417-B1 METHOD FOR FORMING ON-SITE A COATED OPTICAL ARTICLE ESSILOR INT (FR) 2006-08-02 EP claimed
US-20030125467-A1 A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear JSR CORPORATION (JP) 2003-07-03 US claimed
EP-0665252-B1 Two-pack aqueous coating composition KANSAI PAINT CO LTD (JP) 1998-12-16 EP claimed
US-5519089-A ALKOXYSILANE CONTAINING ACRYLIC COPOLYMER AND POLYISOCYANATE KANSAI PAINT CO., LTD. (JP) 1996-05-21 US claimed
EP-0665252-A2 Two-pack aqueous coating composition KANSAI PAINT CO., LTD. (JP) 1995-08-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 TSHR 4144/4885HPGD 3556/4885ALDH1A1 2251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.