Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678956 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10681216 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10680645 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10675329 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10678106 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10678319 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10678812 | 0.89 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10679645 | 0.88 | RAB9A (0.58) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10678625 | 0.88 | RAB9A (0.65) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL10673505 | 0.87 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792570-A | 3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |