Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.66 |
| ▸ | DHODH | Q02127 | 5/20 | 0.62 |
| ▸ | TACR3 | P29371 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679321 | 0.93 | LMNA (0.68) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL1878543 | 0.82 | KDM4E (0.69) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL10674581 | 0.81 | PDE10A (0.55) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL10673312 | 0.80 | PDE10A (0.54) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| Cinchophen SCHEMBL29376617 | 0.80 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| Cinchophen SCHEMBL7588217 | 0.80 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| Cinchophen SCHEMBL25519 | 0.80 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL10673669 | 0.79 | KDM4E (0.57) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL17923232 | 0.79 | MAPT (0.53) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| Cinchophen SCHEMBL4464779 | 0.79 | KDM4E (0.97) | KDM4ELMNASMN1; SMN2PDE10ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |