Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | PGR | P06401 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674315 | 0.91 | MEN1 (0.74) | MEN1KMT2APGRCYP2C19SRC | |
| SCHEMBL9279359 | 0.87 | MEN1 (0.56) | MEN1KMT2APGRCYP2C19HIF1A | |
| SCHEMBL10671529 | 0.86 | MEN1 (0.81) | MEN1KMT2APGRSRCALDH1A1 | |
| SCHEMBL10671773 | 0.85 | MEN1 (0.54) | MEN1KMT2APGRCYP2C19SRC | |
| Roquinimex SCHEMBL42132 | 0.85 | KMT2A (1.00) | MEN1KMT2APGRSRCALDH1A1 | |
| Roquinimex SCHEMBL8169579 | 0.85 | KMT2A (1.00) | MEN1KMT2APGRSRCALDH1A1 | |
| Roquinimex SCHEMBL29359144 | 0.85 | KMT2A (1.00) | MEN1KMT2APGRSRCALDH1A1 | |
| SCHEMBL24172646 | 0.84 | MEN1 (0.71) | MEN1KMT2APGRSRCHIF1A | |
| SCHEMBL10675968 | 0.81 | MEN1 (0.77) | MEN1KMT2APGRSRCHIF1A | |
| SCHEMBL10671888 | 0.80 | MEN1 (0.76) | MEN1KMT2APGRSRCHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738971-A | ENHANCED CELL-MEDIATED IMMUNITY; ANTIARTHRITIC AGENTS; NONTOXIC | AKTIEBOLASET LEO (SE) | 1988-04-19 | — | — | US | disclosed |
| US-4547511-A | FOR ENHANCIN CELL-MEDIATED IMMUNITY | AKTIEBOLAGET LEO (SE) | 1985-10-15 | — | — | US | disclosed |
| EP-0059698-B1 | HETEROCYCLIC CARBOXAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND METHODS OF TREATMENT THEREWITH | AB LEO (SE) | 1985-09-25 | — | — | EP | disclosed |
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |