Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085817 | 0.91 | MEN1 (0.56) | MEN1KMT2APGRCYP2C19HIF1A | |
| SCHEMBL10674909 | 0.87 | MEN1 (0.74) | MEN1KMT2APGRCYP2C19HIF1A | |
| SCHEMBL9269029 | 0.83 | MEN1 (0.46) | MEN1KMT2APGRCYP2C19HIF1A | |
| SCHEMBL9270246 | 0.79 | MEN1 (0.47) | MEN1KMT2APGRCYP2C19HIF1A | |
| SCHEMBL8086963 | 0.78 | GSK3B (0.43) | MEN1KMT2APGRHIF1AGSK3B | |
| SCHEMBL10674315 | 0.78 | MEN1 (0.74) | MEN1KMT2APGRCYP2C19HIF1A | |
| SCHEMBL9266139 | 0.78 | MEN1 (0.54) | MEN1KMT2APGRHIF1AALDH1A1 | |
| SCHEMBL9201791 | 0.78 | KMT2A (0.54) | MEN1KMT2APGRHIF1AALDH1A1 | |
| SCHEMBL9266250 | 0.77 | KMT2A (0.53) | MEN1KMT2APGRHIF1AALDH1A1 | |
| SCHEMBL9287071 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2APGRHIF1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |