Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 15/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669931 | 1.00 | AVPR1A (0.52) | AVPR1AMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL10672540 | 0.83 | AVPR1A (0.55) | AVPR1AMEN1KMT2AADORA3 | |
| SCHEMBL10674647 | 0.83 | AVPR1A (0.55) | AVPR1AMEN1KMT2AADORA3 | |
| SCHEMBL10671312 | 0.83 | AVPR1A (0.55) | AVPR1AMEN1KMT2AADORA3 | |
| SCHEMBL10672548 | 0.83 | AVPR1A (0.55) | AVPR1AMEN1KMT2AADORA3 | |
| SCHEMBL10673554 | 0.83 | AVPR1A (0.59) | AVPR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL10680846 | 0.83 | AVPR1A (0.59) | AVPR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL10674633 | 0.83 | AVPR1A (0.55) | AVPR1AMEN1KMT2AADORA3 | |
| SCHEMBL10671321 | 0.83 | AVPR1A (0.55) | AVPR1AMEN1KMT2AADORA3 | |
| SCHEMBL10673865 | 0.82 | AVPR1A (0.54) | AVPR1AMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751299-A | Optically active β-lactams and method of their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0144840-A2 | Optically active beta-lactams and method of their production | Takeda Chemical Industries, Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |