SCHEMBL1067685

SCHEMBL1067685

N[C@@H](Cc1ccc(O)cc1)C(=O)O[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
MMP2 P08253 1/20 0.45
ALDH1A1 P00352 1/20 0.44
HDAC8 Q9BY41 2/20 0.43
TAAR1 Q96RJ0 3/20 0.43
SLC6A2 P23975 1/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29034485 0.86 ALPI (0.56) SLC7A5MMP2HDAC8
SCHEMBL2800996 0.86 ALPI (0.56) SLC7A5MMP2HDAC8
SCHEMBL28149830 0.84 ALOX15 (0.59) SLC7A5ALDH1A1SLC6A2ESR1
SCHEMBL13396365 0.82 SLC7A5 (0.50) SLC7A5MMP2ALDH1A1HDAC8TAAR1
SCHEMBL1832905 0.80 SLC7A5 (0.48) SLC7A5MMP2ALDH1A1HDAC8
SCHEMBL13396364 0.80 SLC7A5 (0.48) SLC7A5MMP2ALDH1A1HDAC8
SCHEMBL1945444 0.80 SLC7A5 (0.48) SLC7A5MMP2ALDH1A1HDAC8
SCHEMBL14060350 0.80 SLC7A5 (0.48) SLC7A5MMP2ALDH1A1HDAC8TAAR1
SCHEMBL27680265 0.80 SLC7A5 (0.67) SLC7A5HDAC8TAAR1SLC6A2ESR1
SCHEMBL4453960 0.80 SLC7A5 (0.67) SLC7A5HDAC8TAAR1SLC6A2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105525-B Material with function of enriching nitrotyrosine peptide fragments and preparation method and application thereof 湖南师范大学 2023-11-24 CN claimed
EP-2859354-B1 NITRATED CARDIAC TROPONIN I AS A BIOMARKER OF CARDIAC ISCHEMIA FLEURY S A (BR) 2016-09-14 EP claimed
CN-105934240-A Hybrid, composition containing the hybrid, preparation method and use thereof 安杰瑞姆生物科学公司 2016-09-07 CN claimed
EP-2235539-B1 USE OF A PROTEIN OR NITRATED PEPTIDE SEQUENCE FOR IMPLEMENTING A DIAGNOSIS METHOD Université Joseph Fourier (FR) 2016-08-31 EP claimed
EP-2235539-A2 USE OF A PROTEIN OR NITRATED PEPTIDE SEQUENCE FOR IMPLEMENTING A DIAGNOSIS METHOD Université Joseph Fourier (FR) 2010-10-06 EP claimed
WO-2009112670-A2 USE OF A PROTEIN OR NITRATED PEPTIDE SEQUENCE FOR IMPLEMENTING A DIAGNOSIS METHOD UNIVERSITE JOSEPH FOURIER (FR) 2009-09-17 WO claimed
EP-3319984-B1 TAU-BINDING ANTIBODIES UCB Biopharma SRL (BE) 2026-03-11 EP disclosed
CN-116712454-B Multi-dimensional cisplatin nephrotoxicity reducing nanoparticle as well as preparation method and application thereof 中南大学 2025-06-17 CN disclosed
CN-119876395-A DNA methylation marker composition for screening gastric cancer 上海荧测生物科技有限公司 2025-04-25 CN disclosed
EP-3689820-B1 SENSORS COMPRISING MESOPOROUS SILICA PARTICLES KIM YOUNGDO (KR) 2025-03-19 EP disclosed
WO-2024013024-A1 BIOSENSOR FOR DETECTION OF TSH LEVELS HEI THERAPEUTICS APS (DK) 2024-01-18 WO disclosed
EP-4306947-A1 BIOSENSOR FOR DETECTION OF TSH LEVELS HEI Therapeutics ApS (DK) 2024-01-17 EP disclosed
CN-113105525-B Material with function of enriching nitrotyrosine peptide fragments and preparation method and application thereof 湖南师范大学 2023-11-24 CN disclosed
CN-1511258-A Method and kit for following neurodegenerative diseases GEMAC 2004-07-07 CN disclosed
WO-2003076946-A2 DETECTION OF SPECIFIC NITRATED PROTEIN MARKERS UNIVERSITE DE LIEGE (BE) 2003-09-18 WO disclosed
US-6586467-B2 Tyrosine phosphatase inhibitors useful in the treatment or prevention of Type II Diabetes Mellitus ARRAY BIOPHARMA INC. 2003-07-01 US disclosed
EP-1301474-A2 TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS Array Biopharma Inc. (US) 2003-04-16 EP disclosed
US-20020040003-A1 Preparation of phosphatase inhibitors ARRAY BIOPHARMA INC. 2002-04-04 US disclosed
WO-2002004412-A2 TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2002-01-17 WO disclosed
WO-1998051307-A1 METHODS FOR TREATING INFLAMMATION, INFLAMMATORY DISEASES, ARTHRITIS AND STROKE USING pADPRT INHIBITORS OCTAMER, INC. (US) 1998-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040003-A1 Preparation of phosphatase inhibitors PTPRS, PTPRO, PTPRR SLC7A5 2995/4885MMP2 1609/4885ALDH1A1 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.