Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677453 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL9849951 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL14984890 | 0.85 | MEN1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL28001177 | 0.85 | MEN1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL12416860 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL9850054 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL9849940 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL18887676 | 0.79 | TDP1 (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL9850082 | 0.78 | MAOB (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL28001227 | 0.78 | MEN1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748239-A | VASODILATORS | E. R. SQUIBB & SONS, INC. (US) | 1988-05-31 | — | — | US | disclosed |