SCHEMBL10677495

SCHEMBL10677495

CCC(=O)OC1CCC(C2CCC(CC[C@H]3CC[C@H](CC)CC3)CC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.48
NAAA Q02083 3/20 0.37
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
EPHX2 P34913 1/20 0.33
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
EPHX1 P07099 1/20 0.31
TLR4 O00206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10677502 1.00 CYP19A1 (0.48) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10681846 0.95 CYP19A1 (0.51) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10707045 0.95 CYP19A1 (0.51) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10683569 0.90 NAAA (0.40) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10683577 0.90 NAAA (0.40) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL14159010 0.89 CYP19A1 (0.55) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10706820 0.88 NAAA (0.41) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10674869 0.87 NAAA (0.50) CYP19A1NAAAHTTEPHX2MEN1
SCHEMBL10676358 0.87 CYP19A1 (0.46) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT
SCHEMBL10676364 0.87 CYP19A1 (0.46) CYP19A1NAAAAPOBEC3AAPOBEC3GHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4719032-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-12 US disclosed