Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230115 | 0.85 | PARP10 (0.50) | TSHRSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL17802351 | 0.79 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL17802363 | 0.79 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3LMNA | |
| Fumaric Acid SCHEMBL8867077 | 0.77 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3TSHRSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL5999595 | 0.73 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14192004 | 0.72 | AKR1C3 (0.64) | SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL6017403 | 0.72 | AKR1C3 (0.64) | SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL30730198 | 0.72 | AKR1C3 (0.64) | SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL28866121 | 0.72 | BCAT2 (0.65) | BCAT2SLC6A2SLC6A4SLC6A3KMO | |
| SCHEMBL367843 | 0.72 | BCAT2 (0.65) | BCAT2SLC6A2SLC6A4SLC6A3KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786755-A | ANTAGONISTS, ENZYME INHIBITORS, MEDIATOR RELEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4602023-A | Diphenic acid monoamides | WARNER-LAMBERT COMPANY (US) | 1986-07-22 | — | — | US | disclosed |