BCAT2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL791584	0.45	10/20
SCHEMBL263739	1.00	7/20
SCHEMBL265004	0.58	6/20
SCHEMBL265344	0.72	5/20
SCHEMBL263943	0.68	5/20
SCHEMBL264414	0.65	5/20
SCHEMBL264215	0.51	5/20
SCHEMBL290869	0.43	5/20
Toltrazuril (SCHEMBL248912)	0.38	4/20
SCHEMBL150787	0.53	3/20
SCHEMBL151398	0.47	3/20
SCHEMBL1291110	0.40	3/20
SCHEMBL132986	1.00	2/20
SCHEMBL656983	0.88	2/20
SCHEMBL1193435	0.72	2/20
SCHEMBL901580	0.71	2/20
SCHEMBL530285	0.69	2/20
SCHEMBL437231	0.66	2/20
SCHEMBL570758	0.63	2/20
SCHEMBL944091	0.63	2/20

Clinical trials — most relevant to BCAT2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Role of BCAA in Glucose Homeostasis	PHASE4	UNKNOWN
Treatment of Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C	PHASE3	ACTIVE_NOT_RECRUITING
A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA	PHASE1/PHASE2	WITHDRAWN
L-leucine in Diamond Blackfan Anemia Patients	PHASE2	UNKNOWN
Branched-chain Amino Acid Supplementation for Hepatocellular Carcinoma	PHASE2	WITHDRAWN
Investigation of an Amino Acid Supplement on Glucose Levels in Obese Subjects	nan	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects	nan	COMPLETED
Effect of BCAA Supplementation on Muscle Mass, Muscle Quality and Molecular Markers of Muscle Regeneration in CLD Patients	nan	COMPLETED
Alternations in Body Composition of Tonsillectomy Patients During the Recovery Period	nan	UNKNOWN
Resistance Exercise Program and Branched Chain Amino Acid Supplementation in Heart Failure Patients	nan	COMPLETED
Plasma Free Amino Acids in Patients With Hepatic Encephalopathy	nan	UNKNOWN
How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses	nan	RECRUITING
Branched Chained Amino Acid Supplement in Patients Undergoing Lower Limb Bone Cancer Curettage for Bone Metastasis	nan	NOT_YET_RECRUITING
Alternative Substrates in the Critically Ill Subject	nan	COMPLETED
Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes	nan	COMPLETED
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure	nan	UNKNOWN
BCAA in Patients Undergoing Gastric Cancer Surgery	nan	NOT_YET_RECRUITING
Branched Chain Amino Acids Ratio in Medical Foods	nan	COMPLETED
Effect of Branched-chain Amino Acid Supplementation on Muscle Damage	nan	UNKNOWN
Determining the Effect of Protein Quality on Post-exercise Anabolism in Active Youth	nan	UNKNOWN
Impact of Branched-chain Amino Acids in the Development of Insulin Resistance	nan	COMPLETED
Lysine Requirement of Elderly Men and Women Over 60 Years of Age	nan	COMPLETED
Nutritional Intervention for Sarcopenia	nan	COMPLETED
Effects of Branch Chain Amino Acids on Glucose Tolerance in Obese Pre-Diabetic Subjects	nan	COMPLETED
Comparison of Different Weight Loss Diets With Different Protein Content	nan	COMPLETED
The Effects of Sodium Phenylbutyrate on Circulating Branched Chain Amino Acids	nan	COMPLETED
Metabolism of Branched-chain Amino Acids in Monocyte/Macrophage During Sepsis	nan	UNKNOWN
Dietary Intake and Circulating Levels of Branched Chain Amino Acids	nan	COMPLETED
Metabolomics and Bariatric Surgery in Patients With Metabolically Unhealthy Obesity	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a BCAT2 binder may also engage these)

Protein	Name	Similarity
Q5REP0	—	1.000	Q5REP0 →
O35855	—	1.000	O35855 →
O35854	—	1.000	O35854 →
Q5EA40	—	1.000	Q5EA40 →
Q91WM2	—	0.959	Q91WM2 →
P24288	—	0.959	P24288 →
P54690	—	0.959	P54690 →
HDHD5	Haloacid dehalogenase-like hydrolase domain-containing 5	0.959	landscape →
Q9GKM4	—	0.958	Q9GKM4 →
Q14CH1	—	0.956	Q14CH1 →
BCAT1	Branched-chain-amino-acid aminotransferase, cytosolic	0.951	landscape →
A7SLW1	—	0.950	A7SLW1 →
Q96GJ1	—	0.950	Q96GJ1 →
Q5I0L3	—	0.950	Q5I0L3 →
Q921Q3	—	0.950	Q921Q3 →
Q5XIG6	—	0.950	Q5XIG6 →
Q9QZC8	—	0.949	Q9QZC8 →
Q5RFM7	—	0.948	Q5RFM7 →
Q9Y2Z4	—	0.948	Q9Y2Z4 →
Q9FYA6	—	0.947	Q9FYA6 →
Q5R7A2	—	0.947	Q5R7A2 →
Q148G5	—	0.947	Q148G5 →
Q5RK23	—	0.947	Q5RK23 →
Q9JLV6	—	0.947	Q9JLV6 →
Q6P3E7	—	0.946	Q6P3E7 →
Q3T056	—	0.946	Q3T056 →
ALG1	Chitobiosyldiphosphodolichol beta-mannosyltransferase	0.946	landscape →
Q8BZG5	—	0.946	Q8BZG5 →
Q8BQJ6	—	0.945	Q8BQJ6 →
Q8BYL4	—	0.945	Q8BYL4 →