Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 4/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BIRC8 | Q96P09 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291351 | 0.99 | MEN1 (0.41) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11151309 | 0.92 | MAPT (0.46) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11294922 | 0.91 | MAPT (0.46) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10699884 | 0.91 | LMNA (0.43) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11058890 | 0.91 | MAPT (0.40) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11296221 | 0.90 | MAPT (0.39) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11290920 | 0.90 | MAPT (0.40) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11292237 | 0.89 | MAPT (0.39) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10678839 | 0.86 | MAPT (0.35) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10838601 | 0.86 | MEN1 (0.44) | MEN1KMT2ACCKBRMAPTPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775670-A | BACTERICIDES, ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1988-10-04 | — | — | US | claimed |
| US-4775670-A | BACTERICIDES, ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4529698-A | Culturing Chromobacterium | E. R. SQUIBB & SONS, INC. (US) | 1985-07-16 | — | — | US | disclosed |