Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SGPL1 | O95470 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296513 | 0.85 | CYP19A1 (0.52) | CYP26A1CYP19A1 | |
| SCHEMBL7380518 | 0.83 | CYP19A1 (0.41) | ALDH1A1SGPL1S1PR1MCHR1CYP19A1 | |
| SCHEMBL7719725 | 0.83 | PSEN1 (0.46) | CYP2D6ALDH1A1TSHRS1PR1CYP19A1 | |
| SCHEMBL6197173 | 0.81 | MCHR1 (0.45) | ALDH1A1TSHRCYP2C9MAPTMAPK1 | |
| SCHEMBL9630809 | 0.81 | CYP19A1 (0.52) | CYP26A1CYP19A1 | |
| SCHEMBL10529517 | 0.80 | GAA (0.46) | ALDH1A1TSHRCYP2C9MAPTMAPK1 | |
| SCHEMBL7723979 | 0.77 | PSEN1 (0.47) | CYP2D6ALDH1A1CYP3A4CYP2C19MAPK1 | |
| SCHEMBL31267611 | 0.77 | CYP2D6 (0.41) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL4225647 | 0.76 | CYP19A1 (0.47) | ALDH1A1CYP26A1CYP19A1 | |
| SCHEMBL10532540 | 0.75 | GAA (0.46) | ALDH1A1TSHRCYP2C9MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4777257-A | CARDIOVASCULAR DISORDERS | DAIICHI SEIYAKU CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| US-4665188-A | Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecarboxylic acids or corresponding idan-carboxylic acids which are thromboxane A2 | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0135177-A2 | Benzocycloalkane derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-03-27 | — | — | EP | disclosed |