Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARD | Q03181 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678216 | 0.95 | GRM2 (0.50) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL10678950 | 0.89 | CYSLTR2 (0.46) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL11038772 | 0.84 | PPARG (0.59) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL10675071 | 0.83 | CYSLTR2 (0.64) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL11024302 | 0.82 | PPARG (0.51) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL11025084 | 0.82 | PPARG (0.51) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL6244992 | 0.82 | GRM2 (0.72) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL6242750 | 0.81 | GRM2 (0.69) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL10683362 | 0.80 | PPARG (0.55) | GRM2PPARGPPARDPPARAMAPT | |
| SCHEMBL10682742 | 0.79 | GRM2 (0.52) | GRM2PPARGPPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740514-A | Tetrazole substituted compounds and their anti-allergic use | LILLY INDUSTRIES LIMITED (GB) | 1988-04-26 | — | — | US | disclosed |
| US-4595540-A | Benzonitrile and benzothiocyano intermediates | LILLY INDUSTRIES LIMITED (GB) | 1986-06-17 | — | — | US | disclosed |
| EP-0110541-A1 | Organic compounds and their pharmaceutical use | Lilly Industries Limited (GB) | 1984-06-13 | — | — | EP | disclosed |