Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025084 | 1.00 | PPARG (0.51) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11043538 | 0.84 | PPARG (0.72) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11043542 | 0.84 | PPARG (0.72) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL5032476 | 0.84 | GRM2 (0.72) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL5032472 | 0.84 | GRM2 (0.72) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11038772 | 0.82 | PPARG (0.59) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL10678757 | 0.82 | GRM2 (0.52) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL10957649 | 0.79 | GRM2 (0.59) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11022202 | 0.77 | POLB (0.46) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11020870 | 0.77 | POLB (0.46) | PPARGPPARDPPARAGRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056172-B1 | PHENOXY- AND THIOPHENOXY COMPOUNDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-04-03 | — | — | EP | claimed |
| EP-0056172-A2 | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-07-21 | — | — | EP | claimed |
| EP-0056172-B1 | PHENOXY- AND THIOPHENOXY COMPOUNDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-04-03 | — | — | EP | disclosed |
| EP-0056172-A2 | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-07-21 | — | — | EP | disclosed |