Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684965 | 0.87 | L3MBTL1 (0.44) | ALDH1A1GAAKMT2AMEN1BRD4 | |
| SCHEMBL10679584 | 0.87 | L3MBTL1 (0.44) | ALDH1A1GAAKMT2AMEN1BRD4 | |
| SCHEMBL10681724 | 0.87 | L3MBTL1 (0.44) | ALDH1A1GAAKMT2AMEN1BRD4 | |
| SCHEMBL7142586 | 0.81 | PARP1 (0.44) | ALDH1A1GAAKMT2AMEN1BRD4 | |
| SCHEMBL10674600 | 0.81 | L3MBTL1 (0.39) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL10674591 | 0.81 | L3MBTL1 (0.39) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL10676313 | 0.80 | MAPK1 (0.39) | ALDH1A1GAAKMT2AMEN1BRD4 | |
| SCHEMBL10676322 | 0.80 | MAPK1 (0.39) | ALDH1A1GAAKMT2AMEN1BRD4 | |
| SCHEMBL10676465 | 0.75 | MEN1 (0.60) | ALDH1A1GAAKMT2AMEN1MAPK1 | |
| SCHEMBL10678266 | 0.75 | HSD17B10 (0.51) | ALDH1A1GAAKMT2AMEN1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0233728-A1 | 1,4-Benzoxazine derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |