Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471329 | 0.80 | CA12 (0.44) | ALDH1A1POLBHSD17B10MAPK1KDM4E | |
| SCHEMBL23534213 | 0.77 | USP2 (0.52) | ALDH1A1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL8029107 | 0.76 | KMT2A (0.54) | ALDH1A1HSD17B10MAPK1MEN1KMT2A | |
| SCHEMBL8039047 | 0.76 | KMT2A (0.54) | ALDH1A1HSD17B10MAPK1MEN1KMT2A | |
| SCHEMBL9155928 | 0.72 | PARP1 (0.51) | ALDH1A1HSD17B10MAPK1HPGDMEN1 | |
| SCHEMBL28923512 | 0.70 | USP2 (0.53) | ALDH1A1HSD17B10MAPK1MEN1KMT2A | |
| SCHEMBL10679574 | 0.70 | HSD17B10 (0.49) | ALDH1A1HSD17B10MAPK1MEN1KMT2A | |
| SCHEMBL10678266 | 0.68 | HSD17B10 (0.51) | BRD4ALDH1A1POLBHSD17B10MAPK1 | |
| SCHEMBL22446823 | 0.68 | MAPT (0.50) | ALDH1A1POLBHSD17B10MAPK1KDM4E | |
| SCHEMBL31424896 | 0.68 | MEN1 (0.53) | ALDH1A1POLBHSD17B10MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0233728-A1 | 1,4-Benzoxazine derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |