Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468450 | 0.85 | L3MBTL1 (0.62) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL26654694 | 0.83 | HSD17B10 (0.54) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL26654751 | 0.82 | HSD17B10 (0.53) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL10678266 | 0.81 | HSD17B10 (0.51) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL7475254 | 0.79 | HSD17B10 (0.46) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL10683271 | 0.78 | L3MBTL1 (0.43) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL9155928 | 0.77 | PARP1 (0.51) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL26654821 | 0.77 | HSD17B10 (0.47) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL30665888 | 0.76 | PARP1 (0.57) | HSD17B10KMT2AMEN1USP2GAA | |
| SCHEMBL293466 | 0.76 | PARP1 (0.57) | HSD17B10KMT2AMEN1USP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0233728-A1 | 1,4-Benzoxazine derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |