Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.74 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.74 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15399684 | 0.92 | CYP19A1 (0.87) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| SCHEMBL3092795 | 0.85 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL8865557 | 0.85 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL10661787 | 0.84 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| SCHEMBL10975737 | 0.84 | CYP19A1 (0.74) | CYP19A1CYP11B1CYP11B2TBXAS1CYP2A6 | |
| Bromide SCHEMBL27949880 | 0.84 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| Bromide SCHEMBL27949879 | 0.84 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| Hydrochloric Acid SCHEMBL11499390 | 0.81 | CYP19A1 (0.70) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL10531228 | 0.81 | TBXAS1 (1.00) | CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL10671782 | 0.80 | TBXAS1 (0.97) | CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778817-A | INHIBIT THROMBOXANE SYNTHETASE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0194580-A2 | Imidazole derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |