Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773184 | 0.95 | TSHR (0.42) | CTSKTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9773189 | 0.95 | TSHR (0.42) | CTSKTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9773229 | 0.95 | TSHR (0.42) | CTSKTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9773226 | 0.95 | TSHR (0.42) | CTSKTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1858577 | 0.88 | SMN1; SMN2 (0.46) | L3MBTL1PPARGPPARA | |
| SCHEMBL9773201 | 0.88 | SMN1; SMN2 (0.46) | L3MBTL1PPARGPPARA | |
| SCHEMBL5674353 | 0.88 | SMN1; SMN2 (0.46) | L3MBTL1PPARGPPARA | |
| SCHEMBL7375987 | 0.84 | BLM (0.41) | TDP1L3MBTL1ALDH1A1MAPK1PPARG | |
| SCHEMBL7344531 | 0.84 | BLM (0.41) | TDP1L3MBTL1ALDH1A1MAPK1PPARG | |
| SCHEMBL5012826 | 0.84 | BLM (0.41) | TDP1L3MBTL1ALDH1A1MAPK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734410-A | Lactam derivatives and their use as hypotensive agents | SANKYO COMPANY LIMITED (JP) | 1988-03-29 | — | — | US | disclosed |