Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222071 | 0.82 | IDO1 (0.56) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL613175 | 0.82 | IDO1 (0.56) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31408101 | 0.80 | IDO1 (0.73) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16382293 | 0.80 | IDO1 (0.73) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13351491 | 0.79 | IDO1 (0.53) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13318679 | 0.78 | IDO1 (0.56) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7385025 | 0.76 | IDO1 (0.53) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28287055 | 0.75 | IDO1 (0.66) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8469809 | 0.75 | IDO1 (0.66) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27847377 | 0.74 | IDO1 (0.47) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720550-A | Process for producing imidazolylthiophenaldehydes | A. NATTERMANN & CIE GMBH (DE) | 1988-01-19 | — | — | US | claimed |
| EP-0234350-A2 | Process for producing imidazolylthiophenaldehydes | A. Nattermann & Cie. GmbH (DE) | 1987-09-02 | — | — | EP | claimed |