Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.56 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681020 | 0.84 | TRPV1 (0.57) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL9513484 | 0.84 | POLB (0.56) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL10682397 | 0.84 | TRPV1 (0.59) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL13912 | 0.83 | KMT2A (0.75) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL9382745 | 0.83 | MAPT (0.75) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL975489 | 0.83 | MAPT (1.00) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL30620451 | 0.82 | MAPT (1.00) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL6689700 | 0.81 | GFER (1.00) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL429085 | 0.80 | MAPT (0.75) | KMT2AMAPTMEN1KDM4EALDH1A1 | |
| SCHEMBL15800700 | 0.79 | KMT2A (0.72) | KMT2AMAPTMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788196-A | Phenyl piperazine anti-arrhythmia agents | PFIZER INC. (US) | 1988-11-29 | — | — | US | disclosed |