Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | PTGIR | P43119 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | RARG | P13631 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | PTGFR | P43088 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510133 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11720230 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11529543 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11722045 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11725744 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11720265 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11724103 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11725381 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11725738 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR | |
| SCHEMBL11725088 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGER4PTGER2NR4A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737590-A | PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| US-4439365-A | TRIPHENYLMETHOXY ALKENYLMAGNESIUM HALIDES | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| US-4343949-A | PROSTAGLANDIN REARRANGEMENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| US-4293704-A | Novel 2-substituted-3,4-epoxycyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones | AMERICAN CYANAMID COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4237316-A | ISOMERIZATION OF PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4179574-A | PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4123456-A | BRONCHODILATORS, HYPOTENSIVES, ANTIULCER, ANTISECRETORY, MICROBIOCIDES, ANTICONVULSANTS, OXYTOCICS, ANALGESICS, DIURETICS, ANTIINFLAMMATORY, ANTICOAGULANTS | AMERICAN CYANAMID COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4110368-A | PROSTAGLANDINS, BRONCHODILATOR, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4060540-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4007210-A | PROSTANOIC ACID DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3966773-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3932479-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |