Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | BCL9 | O00512 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21433828 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21777065 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL26976962 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL26980348 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21433779 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL21433889 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL9846659 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL2234364 | 1.00 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL1958366 | 0.99 | MGLL (0.60) | MGLLBCL9CTNNB1MAPTHTR2A | |
| SCHEMBL1144551 | 0.96 | MGLL (0.62) | MGLLBCL9CTNNB1MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761404-A | RESPIRATORY SYSTEM DISORDERS, ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0208961-A2 | Phospholipid analogs useful as paf synthesis inhibitors | MERCK & CO. INC. (US) | 1987-01-21 | — | — | EP | disclosed |