Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 19/20 | 0.73 |
| ▸ | CA1 | P00915 | 19/20 | 0.73 |
| ▸ | CA2 | P00918 | 19/20 | 0.73 |
| ▸ | CA9 | Q16790 | 19/20 | 0.73 |
| ▸ | CA3 | P07451 | 12/20 | 0.73 |
| ▸ | CA4 | P22748 | 12/20 | 0.73 |
| ▸ | CA6 | P23280 | 12/20 | 0.73 |
| ▸ | CA5A | P35218 | 12/20 | 0.73 |
| ▸ | CA7 | P43166 | 12/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 12/20 | 0.73 |
| ▸ | CA13 | Q8N1Q1 | 11/20 | 0.73 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574023 | 0.85 | CA12 (1.00) | CA12CA1CA2CA9CA3 | |
| SCHEMBL31717970 | 0.85 | CA12 (1.00) | CA12CA1CA2CA9CA3 | |
| SCHEMBL1809228 | 0.85 | CA1 (1.00) | CA12CA1CA2CA9CA3 | |
| SCHEMBL11759264 | 0.83 | CA12 (0.71) | CA12CA1CA2CA9CA3 | |
| SCHEMBL1809225 | 0.83 | CA12 (0.71) | CA12CA1CA2CA9CA3 | |
| Hydrochloric Acid SCHEMBL11158505 | 0.83 | CA12 (0.96) | CA12CA1CA2CA9CA3 | |
| SCHEMBL10705983 | 0.81 | CA12 (0.49) | CA12CA1CA2CA9CA3 | |
| SCHEMBL13543310 | 0.80 | CA12 (0.67) | CA12CA1CA2CA9CA3 | |
| SCHEMBL11764346 | 0.79 | CA12 (0.65) | CA12CA1CA2CA9CA3 | |
| SCHEMBL11665653 | 0.79 | CA12 (0.65) | CA12CA1CA2CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725600-A | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0168262-A2 | Pyrimidine derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |
| EP-0068407-A1 | Aminosulfonylbenzoic acid derivatives | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-01-05 | — | — | EP | disclosed |
| EP-0068239-A2 | Sulfamoylbenzoic acid derivatives and pharmaceutical compositions comprising same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1983-01-05 | — | — | EP | disclosed |