SCHEMBL574023

SCHEMBL574023

NS(=O)(=O)c1cc(C(=O)O)c(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 13/20 1.00
CA1 P00915 13/20 1.00
CA2 P00918 13/20 1.00
CA9 Q16790 13/20 1.00
CA4 P22748 10/20 1.00
CA6 P23280 10/20 1.00
CA7 P43166 10/20 1.00
CA13 Q8N1Q1 10/20 1.00
CA14 Q9ULX7 10/20 1.00
CA5B Q9Y2D0 10/20 1.00
CA3 P07451 9/20 1.00
CA5A P35218 8/20 1.00
CISD1 Q9NZ45 5/20 1.00
MEN1 O00255 1/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
KMT2A Q03164 1/20 0.57
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31717970 1.00 CA12 (1.00) CA12CA1CA2CA9CA4
Hydrochloric Acid SCHEMBL11158505 0.98 CA12 (0.96) CA12CA1CA2CA9CA4
SCHEMBL11232241 0.87 CISD1 (0.77) CA12CA1CA2CA9CA4
SCHEMBL3040620 0.85 CISD1 (0.74) CA12CA1CA2CA9CA4
SCHEMBL22499516 0.85 CA12 (0.74) CA12CA1CA2CA9CA4
SCHEMBL11198069 0.85 CISD1 (0.74) CA12CA1CA2CA9CA4
SCHEMBL10685397 0.85 CA12 (0.73) CA12CA1CA2CA9CA4
SCHEMBL1809228 0.85 CA1 (1.00) CA12CA1CA2CA9CA4
SCHEMBL11711824 0.84 CISD1 (0.72) CA12CA1CA2CA9CA4
SCHEMBL2876194 0.84 CISD1 (0.72) CA12CA1CA2CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-3328833-B1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE UNIV VILNIUS (LT) 2025-08-06 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-116178317-A Furosemide production process 台山市新宁制药有限公司 2023-05-30 CN claimed
CN-112142833-B Furosemide artificial antigen, antibody and application thereof in detection of furosemide 华南农业大学 2021-10-29 CN claimed
CN-112142833-A Furosemide artificial antigen, antibody and application thereof in detection of furosemide 华南农业大学 2020-12-29 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
EP-1747229-A1 STEROID PRODRUGS WITH ANDROGENIC EFFECT Schering Aktiengesellschaft (DE) 2007-01-31 EP claimed
WO-2005113575-A1 STEROID PRODRUGS WITH ANDROGENIC EFFECT SCHERING AKTIENGESELLSCHAFT (DE) 2005-12-01 WO claimed
EP-0132540-A1 Antiviral compositions Mochida Pharmaceutical Co., Ltd. (JP) 1985-02-13 EP claimed
EP-0068408-A1 Antiviral compositions and a method for treating virus diseases Mochida Pharmaceutical Co., Ltd. (JP) 1983-01-05 EP claimed
EP-0068407-A1 Aminosulfonylbenzoic acid derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 1983-01-05 EP claimed
JP-57212154-A None JP disclosed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 US disclosed
JP-S57212154-A NOVEL AMINOSULFONYLBENZOIC ACID DERIVATIVE HODOGAYA CHEM CO LTD 1982-12-27 JP disclosed
US-4001284-A PRIMARY AMINES, 2,4-DIPHENOXY-5-SULFAMOYLBENZOIC ACID HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS CA12 4479/4885CA1 4047/4885CA2 3509/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC CA12 658/4885CA1 1546/4885CA2 672/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS CA12 4479/4885CA1 4047/4885CA2 3509/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS CA12 4479/4885CA1 4047/4885CA2 3509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.