Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12863439 | 0.85 | ALDH1A1 (0.63) | CXCR2CXCR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL839476 | 0.84 | ALDH1A1 (0.57) | CXCR2CXCR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5445067 | 0.80 | ALDH1A1 (0.65) | CXCR2CXCR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5846781 | 0.79 | CXCR2 (1.00) | CXCR2CXCR1KDM4E | |
| SCHEMBL796738 | 0.78 | ALDH1A1 (0.57) | CXCR2CXCR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL417669 | 0.78 | ALDH1A1 (0.57) | CXCR2CXCR1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16456689 | 0.78 | CXCR1 (0.51) | CXCR2CXCR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4432631 | 0.77 | ALDH1A1 (0.65) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL796408 | 0.74 | ALDH1A1 (0.61) | CXCR2CXCR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13787819 | 0.74 | ALDH1A1 (0.61) | CXCR2ALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |