Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.64 |
| ▸ | TYMP | P19971 | 7/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18042131 | 0.94 | ADORA1 (0.64) | ADORA1TYMPNT5ETRDMT1ADORA3 | |
| SCHEMBL16715145 | 0.93 | ADORA1 (0.75) | ADORA1TYMPTRDMT1SMN1; SMN2 | |
| SCHEMBL1068571 | 0.93 | ADORA1 (0.75) | ADORA1TYMPTRDMT1SMN1; SMN2 | |
| SCHEMBL8359104 | 0.93 | ADORA1 (0.75) | ADORA1TYMPTRDMT1SMN1; SMN2 | |
| SCHEMBL15993919 | 0.93 | ADORA1 (0.75) | ADORA1TYMPTRDMT1SMN1; SMN2 | |
| SCHEMBL21905178 | 0.89 | ADORA1 (0.62) | ADORA1TYMPNT5ETRDMT1 | |
| SCHEMBL29799117 | 0.89 | NT5E (0.65) | ADORA1TYMPNT5E | |
| SCHEMBL22930672 | 0.88 | TYMP (0.61) | ADORA1TYMPNT5ETRDMT1 | |
| SCHEMBL19127994 | 0.86 | TYMP (0.59) | ADORA1TYMPNT5ETRDMT1DOT1L | |
| SCHEMBL31670489 | 0.86 | TYMP (0.59) | ADORA1TYMPNT5ETRDMT1DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005595-A2 | 2-5A ANALOGS AND THEIR METHODS OF USE | ALIOS BIOPHARMA, INC. (US) | 2011-01-13 | — | — | WO | disclosed |