Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | AHCY | P23526 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.49 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31670489 | 1.00 | TYMP (0.59) | TYMPADORA1CARM1NT5EAHCY | |
| SCHEMBL16715145 | 0.88 | ADORA1 (0.75) | TYMPADORA1TRDMT1 | |
| SCHEMBL8359104 | 0.88 | ADORA1 (0.75) | TYMPADORA1TRDMT1 | |
| SCHEMBL1068571 | 0.88 | ADORA1 (0.75) | TYMPADORA1TRDMT1 | |
| SCHEMBL15993919 | 0.88 | ADORA1 (0.75) | TYMPADORA1TRDMT1 | |
| SCHEMBL20637781 | 0.88 | ADORA1 (0.50) | TYMPADORA1CARM1NT5EAHCY | |
| SCHEMBL1068575 | 0.86 | ADORA1 (0.64) | TYMPADORA1NT5EDOT1LTRDMT1 | |
| SCHEMBL19127268 | 0.85 | TYMP (0.63) | TYMPNT5E | |
| SCHEMBL29799117 | 0.85 | NT5E (0.65) | TYMPADORA1NT5E | |
| SCHEMBL18042131 | 0.85 | ADORA1 (0.64) | TYMPADORA1NT5ETRDMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11505571-B2 | Compounds and compositions for treating conditions associated with sting activity | INNATE TUMOR IMMUNITY, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| US-20210147467-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | INNATE TUMOR IMMUNITY INC (US) | 2021-05-20 | — | — | US | disclosed |
| US-10961270-B2 | Compounds and compositions for treating conditions associated with sting activity | INNATE TUMOR IMMUNITY, INC. (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200165288-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | INNATE TUMOR IMMUNITY INC (US) | 2020-05-28 | — | — | US | disclosed |
| EP-3402801-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | Innate Tumor Immunity, Inc. (US) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961270-B2 | Compounds and compositions for treating conditions associated with sting activity | STING1, CGAS, IRF3 | TYMP 2613/4885ADORA1 842/4885CARM1 2608/4885 |
| US-20200165288-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | TYMP 2613/4885ADORA1 842/4885CARM1 2608/4885 |
| US-11505571-B2 | Compounds and compositions for treating conditions associated with sting activity | STING1, CGAS, IRF3 | TYMP 2613/4885ADORA1 842/4885CARM1 2608/4885 |
| US-20210147467-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | TYMP 2613/4885ADORA1 842/4885CARM1 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.