Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16163258 | 0.86 | L3MBTL1 (0.51) | KMT2AALDH1A1MAPTMEN1GAA | |
| SCHEMBL30100711 | 0.80 | L3MBTL1 (0.53) | KMT2AALDH1A1MAPTMEN1GAA | |
| SCHEMBL16163267 | 0.80 | L3MBTL1 (0.53) | KMT2AALDH1A1MAPTMEN1GAA | |
| SCHEMBL29558351 | 0.71 | GSK3A (0.65) | POLBKMT2AALDH1A1MAPTELANE | |
| SCHEMBL4791747 | 0.71 | GSK3A (0.65) | POLBKMT2AALDH1A1MAPTELANE | |
| SCHEMBL578257 | 0.70 | POLB (0.73) | POLBKMT2AALDH1A1USP2MAPT | |
| SCHEMBL31430235 | 0.70 | NOTUM (0.41) | POLBKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL30597487 | 0.70 | POLB (0.73) | POLBKMT2AALDH1A1USP2MAPT | |
| SCHEMBL30905277 | 0.70 | POLB (0.82) | POLBKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL13309470 | 0.70 | GSK3A (0.50) | KMT2AALDH1A1ELANEMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |