Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680579 | 0.96 | MAPK14 (0.36) | MTNR1AMTNR1BMAPK14KDM4EMEN1 | |
| SCHEMBL10681397 | 0.92 | PLA2G2D (0.41) | MTNR1AMTNR1BLTB4RPLA2G2DALDH1A1 | |
| SCHEMBL10684523 | 0.88 | PLA2G2D (0.40) | KDM4ELTB4RPLA2G2DALDH1A1 | |
| SCHEMBL10689346 | 0.87 | PPARA (0.34) | MTNR1AMTNR1BNPSR1LTB4RPLA2G2D | |
| SCHEMBL10366527 | 0.86 | KDM4E (0.39) | MTNR1AMTNR1BKDM4EMAPTPTGER4 | |
| SCHEMBL10682398 | 0.84 | KDM4E (0.43) | MTNR1AMTNR1BMAPK14KDM4EMEN1 | |
| SCHEMBL10680185 | 0.84 | BPTF (0.40) | KDM4EGAATSHRKMT2AHSD17B10 | |
| SCHEMBL10368098 | 0.83 | KDM4E (0.43) | MTNR1AMTNR1BKDM4ELTB4RPLA2G2D | |
| SCHEMBL10366155 | 0.82 | KDM4E (0.40) | MTNR1AMTNR1BKDM4ELTB4RPLA2G2D | |
| SCHEMBL10368185 | 0.80 | PTGER4 (0.41) | KDM4EMEN1GAAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | claimed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | claimed |