Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20898306 | 0.86 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL27636164 | 0.84 | ALDH1A1 (0.57) | USP2PLA2G2CCES2ALDH1A1HTT | |
| SCHEMBL20898182 | 0.84 | USP2 (0.64) | USP2PLA2G2CHTTLPAR5MEN1 | |
| SCHEMBL22287251 | 0.83 | USP2 (0.63) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL21046030 | 0.82 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL21046040 | 0.82 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL21046008 | 0.82 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL16367888 | 0.82 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL21046022 | 0.82 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT | |
| SCHEMBL21046018 | 0.82 | USP2 (0.68) | USP2PLA2G2CCES2PRKCAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761404-A | RESPIRATORY SYSTEM DISORDERS, ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0208961-A2 | Phospholipid analogs useful as paf synthesis inhibitors | MERCK & CO. INC. (US) | 1987-01-21 | — | — | EP | disclosed |