Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686554 | 1.00 | CRBN (0.39) | CRBNDDB1PARP1TDP1L3MBTL1 | |
| SCHEMBL10377762 | 0.85 | CRBN (0.37) | CRBNPARP1PARP10HSD17B3 | |
| SCHEMBL10377761 | 0.85 | CRBN (0.37) | CRBNPARP1PARP10HSD17B3 | |
| SCHEMBL10687019 | 0.82 | CRBN (0.40) | CRBNDDB1PARP1TDP1L3MBTL1 | |
| SCHEMBL10379185 | 0.81 | ACHE (0.45) | CRBNMETAP1 | |
| SCHEMBL10379186 | 0.81 | ACHE (0.45) | CRBNMETAP1 | |
| SCHEMBL10378789 | 0.81 | CRBN (0.46) | CRBNL3MBTL1 | |
| SCHEMBL10378790 | 0.81 | CRBN (0.46) | CRBNL3MBTL1 | |
| SCHEMBL10688848 | 0.79 | CRBN (0.36) | CRBN | |
| SCHEMBL10688845 | 0.79 | CRBN (0.36) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | disclosed |