SCHEMBL1068664

SCHEMBL1068664

COc1c[c]ccc1C(F)F

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1081435 0.84 CA12 (0.31) CA12CA1CA2CA4CA7
SCHEMBL16950980 0.82 POLB (0.35) CA12CA1CA2CA4CA7
SCHEMBL25385566 0.81 ALDH1A1 (0.33)
SCHEMBL1065162 0.80
SCHEMBL221692 0.80 CYP2D6 (0.32) CA12CA1CA2CA4CA7
SCHEMBL1066640 0.77 PDE2A (0.30)
SCHEMBL27587317 0.77 CA1 (0.43) CA12CA1CA2CA4CA7
SCHEMBL11619813 0.76 TSHR (0.36)
SCHEMBL1067896 0.74 PDE4B (0.36) CA12CA1CA2CA4CA7
SCHEMBL1062938 0.74 PDE4B (0.36) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011006886-A2 AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV BASF SE (DE) 2011-01-20 WO disclosed
WO-2010149758-A1 ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES BASF SE (DE) 2010-12-29 WO disclosed